Silver nanoparticles as an antibacterial agent for endodontic infections

Materials and method Silver nanoparticles have gained more attention owing to their broad spectrum of antibacterial activity and low cost of manufacturing. In the present study, starch coated silver nanoparticle were synthesized and characterized by SEM/ EDX and UV/Vis spectroscopy. Starch coated nanosilver was tested for their antibacterial activity against various microorganisms that are commonly found in endodontic failures such as Enterococcus faecalis, Escherichia coli, Staphylococcus aureus, Streptococcus pneumoniae, Acinetobacter baumani, Candida albicans, Klebsiella pneumonia. The antibacterial activities were assessed in vitro by 1) Agar diffusion test (ADT) 2) MIC by spectroscopic method 3) efficacy assessment using dentinal tubule model at depths of 200 μm and 400 μm in extracted single rooted teeth.